A widely used drug in Ayurveda, gaining ever-growing popularity in modern times. A. indica, the next important ingredient in KARNIM shows its anti-diabetic action by stimulating the insulin secretion by the B-cells of Islet of Langerhans of the pancreas in a manner similar 5 to the sulfonylureas like chlorpropamide .

One of the active principles is Nimbin. Besides correcting diabetes by increasing the insulin levels in blood crculation, A. indica also 13 normalizes the body’s immune system that deteriorates in diabetic 12 conditions due to loss of body proteins .